Sleep Better, Naturally

Restful sleep is vital to health and well-being, as are a healthy diet and exercise.

SLEEP is a supplement developed by Apphia Laboratories clinically proven to:

  • Promotes healthy, uninterrupted sleep patterns
  • Promotes restful sleep
  • Helps support circadian rhythms & immune function

SLEEP Ingredients

Ganoderma lucidum mushroom mycelium

Reishi mushroom supports healthy endocrine functions in the body, which regulate hormones like melatonin and cortisol. Reishi is known as a nervine, a type of herb that supports nervous system, promoting relaxation and preparing the body for restful sleep.

Humulus lupulus (Hop)

Humulus lupulus (Hop) has different properties: calming, sleep inducing, gastric secretion stimulating, and spasmolytic. Increasing GABAergic activity seems to be the main mechanism of action, thus inhibiting the central nervous system. Moreover, hop has demonstrated binding affinities to some of the melatonin (ML1 and ML2) and serotonin (5-HT4e, 5-HT6 and 5-HT7) receptor subtypes that are involved in circadian rhythm and sleep regulation.

Vitamin B6

Vitamin B6 benefits the body by converting the amino acid tryptophan into serotonin, a neurotransmitter that helps regulate levels of the sleep hormone melatonin.


Melatonin is a hormone that’s naturally made by the pineal gland. It helps you fall asleep by calming the body before bed. Melatonin works together with your body’s circadian rhythm. In simple terms, the circadian rhythm is your body’s internal clock. Melatonin also helps regulate your body temperature, your blood pressure, and the levels of some hormones. Melatonin levels start to rise in your body when it’s dark outside, signaling to your body that it’s time to sleep.

SLEEP Benefits

SLEEP  is a Food Supplement formulated to promote relaxation and healthy sleep cycle.

  • Promotes healthy, uninterrupted sleep patterns
  • Promotes restful sleep
  • Helps support circadian rhythms & immune function

Recommended for Adults

It is suitable for long-term use in adults of all age groups.

One Capsule Per Day

Take 1 capsule 30 minutes before going to sleep

Each bottle contains a 30-day supply.

No Animal Products

Vegetarian, vegan, gluten-free, nut-free, no artificial colors or flavors.

EU and EFSA recommendations

The product is manufactured under Good Manufacturing Practice (GMP) process and meets EFSA regulatory criteria.

Apphia Laboratories S.r.l.

Via Casilina Sud 69/E, 03013 Ferentino (FR), Italy


Tel: +39 0775 1831004

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