It’s time for your Menopause Transformation

KHELMA LONGEVITY MENOPAUSE FORMULA is a Food Supplement scientifically formulated to support cellular health and optimal hormone balance

For women, menopause is a natural part of getting older, but it may also speed up the aging process.

MENOPAUSE FORMULA contains extracts of Cimicifuga racemosa, Glicine max bioactive polyphenolic extracts from Vitis vinifera, Olea europea, accinium myrtillus and K-age™ an innovative synergistic complex, obtained from Polygonum cuspidatum and Olea europea which provides biologically enhanced trans-Resveratrol.

MENOPAUSE FORMULA through the synergistic action of the above compounds helps to  promote female hormonal balance and  support symptomatic relief of menopause.


K-age™ is an innovative proprietary synergistic complex obtained from Polygonum cuspidatum and Olea europea which provides biologically enhanced trans-Resveratrol.
K-age™ aims to prevent and repair cellular damage caused by free radicals, protects cells from Oxidative stress, stimulates the regeneration of cells and prevents the accumulation of damaged components in the cell by increasing proteasome levels and decreasing the levels of oxidized proteins.

Olea europea (fruits)

Olive Polyphenols prevent and repair cellular damage caused by free radicals, prevent oxidation of low density lipoproteins, reduce the risk of coronary heart disease, improve glucose metabolism and skin health. More recently, studies have revealed that olive polyphenols  are related also other important  activities including anti-amyloidogenic activity, cell signaling modulation, effects on telomere length and modulation of the sirtuin proteins. Olive Polyphenols are able to cross the blood—brain barrier with multiple effects on pathways involved in neurodegeneration and ageing may be proven efficacious in the treatment of age-related diseases such as Alzheimer’s disease.

Resveratrol from Polygonum cuspidatum (root)

Resveratrol a powerful polyphenol found in several types of plants, including red grapes, blueberries, and nuts. Resveratrol works inside every cell in the body to help rejuvenate the mitochondria, the powerhouses that keep cells functioning properly.
Scientific evidence suggests that it can also help promote healthy aging in humans and animals. Several lab studies have shown that it may improve cellular health, in particular by activating sirtuins Resveratrol is drawing a lot of attention in the scientific community with over 1100 studies published in 2016 alone; the total number of publications on resveratrol now exceeds 10,000, making it one of the fastest growing bodies of evidence for a health and wellness ingredient. This published research and clinical data suggests that resveratrol can play a role in healthy aging through maintaining bone health, cardiovascular health, blood glucose control, healthy cognitive function, skin youthfulness and oral health.

Vitis vinifera (fruits)

The dietary consumption of grape and its products is associated with a lower incidence of degenerative diseases such as cardiovascular disease and certain types of cancers. Most recent interest has focused on the bioactive phenolic compounds in grape. Anthocyanins, flavanols, flavonols and resveratrol are the most important grape polyphenols because they possess many biological activities, such as antioxidant, cardioprotective, anticancer, anti-inflammation, antiaging and antimicrobial properties.

Soy Isoflavones from Glysine max (seeds)

Soy Isoflavones, are bioflavonoids found in soy products and other plants that are able to interact with various hormones such as estrogen.
When estrogen levels begin to fall during menopause, the normal balance of hormones becomes disrupted. A myriad of symptoms may accompany the drop in estrogen, including hot flashes, night sweats, loss of memory and irritability. Many women are wary of beginning hormone replacement therapy because of the risks associated with it. According to, “Overall, evidence suggests that soy products containing isoflavones may help reduce menopausal symptoms, such as hot flashes. Soy consumption has been suggested to exert potentially cancer-preventive effects in premenopausal women, such as increased menstrual cycle length and sex hormone-binding globulin levels and decreased estrogen levels.

Olea europea (leafs)

Olive leaf extract comes from the leaves of olive plants, and is distinct from olive oil; the leaf extract contains phenolics such as oleuropein, and appears to have highly protective effects against LDL oxidation and may also benefit glucose metabolism and skin health.

Olive phenolics in general, which are present in high levels in olive leaf extract, appear to potently protect LDL cholesterol from oxidation. This is attributed to the anti-inflammatory effects of hydroxytyrosol, and appears to be active at a low enough dose to apply to consumption of olive product consumption. Olive leaf may also influence levels of lipoproteins in a beneficial manner (LDL, HDL, total cholesterol, although the actual changes in lipoprotein content is rather small. Overall, olive phenolics are more anti-artherosclerotic than they are cholesterol reducing.

Vaccinium myrtillus (fruits)

Bilberry is one of the richest natural sources of anthocyanins. These polyphenolic components give bilberry its blue/black color and high antioxidant content, and they are believed to be the key bioactives responsible for the many reported health benefits of bilberry. It has been reported to lower blood glucose, to have anti-inflammatory and lipid-lowering effects, and to promote antioxidant defense and lower oxidative stress. Therefore, bilberry is of potential value in the treatment or prevention of conditions associated with inflammation, dyslipidemia, hyperglycemia or increased oxidative stress, cardiovascular disease (CVD), cancer, diabetes, and dementia and other age-related diseases. There are also reports that bilberry has antimicrobial activity.

Cimicifuga Racemosa (root)

Black cohosh (Cimicifuga racemosa) is a North American perennial herb that has been used to treat gynecological complaints for centuries. Recognized for its mild sedative and anti-inflammatory activity, black cohosh can help with hot flashes and other symptoms associated with that dramatic change of life called menopause. Black cohosh is an herb used to treat perimenopause and menopause symptoms. In particular, these symptoms include hot flashes, sleep disturbances moodiness, vaginal dryness, decreased sex drive or motivation and excessive sweating. It is non-estrogenic (despite being thought to influence estrogen in the past) and may act centrally (in the brain) via serotonin, dopamine or opioids.


MENOPAUSE FORMULA is a Food Supplement formulated to support cellular health and optimal hormone balance.

  • Maintains healthy estrogen metabolism during menopause
  • Reduces and prevents hot flashes , night sweats and sleeplessness
  • Relieves anxiety and improves mood
  • Boost libido and sex drive
  • Prevent and repair Cellular Senescence
  • Protects cells from Oxidative Stress

Recommended for Adults

Created for long-term use in adults of all ages.

1 or 2 Capsules Daily According to Needs

We recommend 1 or 2 capsules daily, with or without food.

No Animal Products

Vegetarian, vegan, gluten-free, nut-free, and contains no artificial colors or flavors.

EU and EFSA recommendations

The products are manufactured under Good Manufacturing Practice (GMP) protocols and meet current EU legislation and EFSA regulation and guidance.

Apphia Laboratories S.r.l.

Via Casilina Sud 69/E, 03013 Ferentino (FR), Italy


Tel: +39 0775 1831004

© Copyrigth 2021 Apphia Laboratories Cookies