EF ZIN contains Resveratrol from Polygonum cuspidatum root, a powerful polyphenol found also in several types of plants, including red grapes, blueberries, and nuts. Resveratrol works inside every cell in the body to help rejuvenate the mitochondria, the powerhouses that keep cells functioning properly. Several lab studies have shown that it may improve metabolic health, in particular by activating sirtuins. The Resveratrol contained in the EF ZIN, favorably enhances the activation of cellular sirtuin proteins (longevity factors). NAD+ is required for our sirtuins to function. As we age, NAD+ levels plummet, which impedes the ability of resveratrol to deliver its benefits. When sirtuins are activated, the end result is delayed ageing, which has been demonstrated in a wide spectrum of experimental models, including mammals. Sirtuins that are activated by resveratrol require NAD+ as their energy substrate. Loss of NAD+ impedes beneficial sirtuin function. Younger people have high NAD+ levels that enable them to benefit from the sirtuin-boosting effects of resveratrol. To improve the functionality of sirtuin proteins, it makes sense for maturing individuals to boost their NAD+ levels. The good news is that a precursor to NAD+ can be found in Vitamin B3. The dosage recommendation of EF ZIN can enable older people to restore cellular NAD+ to more youthful profiles.