KHELMA LONGEVITY

An holistic and personalized approach to prevent, maintain and improve health

As the body ages, its cells and communication systems become less balanced and efficient, which leads to greater production of free radicals and increased signaling of inflammatory cytokines and, thus, deterioration of cells and tissues. This, in turn, can greatly influence noticeable qualities like brain acuity, vision, pain and skin integrity, and also make conditions more favorable for cancer or chronic inflammation, the precursor to the majority of disease states.

Khelma Longevity line of Food Supplements enhances health-span by optimizing long term Cellular Health and target specific health concerns including general wllbeing, energy production, immune health, eye health, menopause health, stress relief and weight management. Khelma Longevity products improve Quality of Life better than other form of supplementation. This Quality of Life improvement is closely related with Cellular Aging. Optimal Cellular Health can maintain youth in young bodies or reverse the ravages of time for those who are in their more mature years.

Multipath Antiaging intervention strategy

Our approach is that a multipath intervention strategy targeting multiple aging pathways may promote overall health.

With the KHELMA LONGEVITY products and their unique composition, we target a critical number of well-known pathways related to health, fitness, and longevity: DNA damage, epigenetic factors, telomere erosion, mitochondrial dysfunction, proteasome function, diet or exercise induced inflammation, insulin-like growth factors, autophagy, vascular circulation, neural function, and oxidative stress.

Our Scientific Evidence

Anti-ageing properties of Khelma LongevityTM: treatment of human fibroblasts increases proteasome levels and decreases the levels of oxidized proteins.

In vitro pilot study indicates that Khelma Longevity™ is a potent proteasome activator demonstrating clear anti-ageing properties. The study is published in 25 September 2017 in  New Biotechnology, special issue in memory of professor Brian F.C. Clark (1936-2014) : New Biotechnology is the official journal of the European Federation of Biotechnology (EFB).

The study, determined the putative anti-ageing properties of Khelma Longevity™, a formula based on various natural compounds from the Mediterranean area. Human primary fibroblast cultures were treated with a wide range of concentrations of Khelma Longevity™ for 1 day or 3 consecutive days. Following these treatments, two major and complementary biomarkers of ageing were measured, namely, the proteasome and the amount of oxidized proteins. It was observed that 24 h of treatment with Khelma Longevity™ resulted in a maximum increase of about 41% of the total protein levels of 20S proteasome. Levels of oxidized proteins were reduced by almost 6.5-fold following longer treatments. Specifically we have observed a maximum decrease of protein carbonyls to 84.7% in comparison with nontreated control cells following 3 days of continuous treatment with Khelma Longevity™. These results support the notion that formulas rich in natural compounds from the Mediterranean area possess anti-ageing properties.

Published Scientific Studies

Anti-ageing properties of Khelma Longevity™

Anti-ageing properties of Khelma Longevity™: treatment of human fibroblasts increases proteasome levels and decreases the levels of oxidized proteins.

In vitro pilot study indicates that Khelma Longevity™ is a potent proteasome activator demonstrating clear anti-ageing properties. The study is published in 25 September 2017 in  New Biotechnology, special issue in memory of professor Brian F.C. Clark (1936-2014) : New Biotechnology is the official journal of the European Federation of Biotechnology (EFB).

How does KHELMA LONGEVITY works at the Cellular level

KHELMA LONGEVITY

Khelma Longevity Food Supplements are a holistic and personalized approach to preventing, maintaining and improving quality of life. They provide specially targeted benefits to specific health categories such as general well-being, energy production, immune protection, vision protection, menopause, stress and weight management. At the same time, they promote the optimization of cellular health by contributing to the prevention and repair of cellular damage caused by free radicals, to the protection of cells from oxidative stress, to the rejuvenation of cells by preventing the accumulationof damaged components in the cells by increasing proteasome levels and decreasing the levels of oxidizized proteins.

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